Charles J. Epstein was educated at Harvard College and Harvard Medical School and trained in internal medicine at the Peter Bent Brigham Hospital, in medical genetics at the University of Washington, and in biochemistry at the National Institutes of Health. Since 1967, he has been at the University of California, San Francisco, where he is Emeritus Professor of Pediatrics and Chief of the Division of Medical Genetics in Pediatrics.
Dr. Epstein is a member of the Institute of Medicine. He has served as President of the American Society of Human Genetics, President of the American Board of Medical Genetics, Chairman of the Residency Review Committee for Medical Genetics, Editor of the American Journal of Human Genetics, and as a member of the Recombinant DNA Advisory Committee (the RAC) of the National Institutes of Health. In 2001 he received the William Allan Award from the American Society of Human Genetics, and in 2004 he was elected Fellow of the American Academy of Arts and Sciences.
Dr. Epstein’s major research interests have been in the biochemistry and genetics of early embryonic development, the pathogenesis of Down syndrome, and genetic approaches to the study of free radical defense mechanisms.